Basal DNA repair machinery is subject to positive selection in ionizing-radiation-resistant bacteria

doi:10.1186/1471-2164-9-297

BMC Genomics

Volume 9

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Research article

Basal DNA repair machinery is subject to positive selection in ionizing-radiation-resistant bacteria

Haïtham Sghaier¹^* , Kaïs Ghedira²^* , Alia Benkahla² and Insaf Barkallah¹

¹Unit of Microbiology and Molecular Biology, National Center for Nuclear Sciences and Technologies (CNSTN), Sidi Thabet Technopark, 2020 Sidi Thabet, Tunisia

²Group of Bioinformatics and Modelling, Laboratory of Immunology, Vaccinology, and Molecular Genetics, Institute Pasteur of Tunis, 13, place Pasteur BP 74, 1002 Tunis, Tunisia

author email corresponding author email* Contributed equally

BMC Genomics 2008, 9:297doi:10.1186/1471-2164-9-297


Published:	21 June 2008

Additional files

Additional file 1:

Common genes in ionizing-radiation-resistant bacteria (IRRB) and positive Darwinian selection. Bold letters denote genes under positive selection, whilst non-bold letters denote genes under neutral or purifying selection. Light gray shading indicates genes under positive selection in IRRB and under neutral or purifying selection in IRSB. Dark gray shading indicates genes that are under positive selection in IRRB for which orthologs are absent in all IRSB (see Methods).

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Additional file 2:

Alignment of sets of orthologs in ionizing-radiation-resistant bacteria (IRRB). Sets of orthologs present in all IRRB were aligned with CLUSTAL W following detection with MultiParanoid (see Methods).

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Additional file 3:

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Additional file 9:

Alignment of sets of orthologs in ionizing-radiation-sensitive bacteria (IRSB) for which there are orthologs in all IRRB. Sets of orthologs present in all IRSB, and for which there are orthologs in all IRRB, were aligned with CLUSTAL W following detection with MultiParanoid (see Methods).