Gene expression responses to the suppression of Pou5f1 (A) or Sox2 (B) expression in ES cells. Time and magnitude of responses were estimated from the time course microarray data using 1.5-fold expression changes as a threshold (C), and then used as coordinates in a scatter-plot. Tentative target genes were identified as shown in Fig 1.
Sharov et al. BMC Genomics 2008 9:269 doi:10.1186/1471-2164-9-269