Additional file 7.

The three populations, CD3+, CD4+ and CD8+ T cells, shared largely conserved expression patterns for the significant genes, demonstrated by the hierarchical clustering (using the Euclidian distance metric) of the combined 4167 significant genes upon T-cell activation in CD3+, CD4+ and CD8+ T-cell populations (average of three biological-replicate experiments for each population). Color denotes degree of differential expression comparing to 0 hour (saturated red = 3-fold upregulation, saturated green = 3-fold down-regulation, black = unchanged, gray = no data available).

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Wang et al. BMC Genomics 2008 9:225   doi:10.1186/1471-2164-9-225