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Open AccessResearch article

Genomic and bioinformatics analysis of human adenovirus type 37: New insights into corneal tropism

Christopher M Robinson1,3 email, Fatemeh Shariati1,2 email, Allison F Gillaspy3,5 email, David W Dyer3,5 email and James Chodosh1,2,3,4 email

1Molecular Pathogenesis of Eye Infection Research Center, Dean A. McGee Eye Institute, 608 Stanton L. Young Blvd., Oklahoma City, OK 73104, USA

2Department of Ophthalmology, University of Oklahoma Health Sciences Center, 1100 North Lindsay, Oklahoma City, OK 73104, USA

3Department of Microbiology & Immunology, University of Oklahoma Health Sciences Center, 1100 North Lindsay, Oklahoma City, OK 73104, USA

4Department of Cell Biology, University of Oklahoma Health Sciences Center, 1100 North Lindsay, Oklahoma City, OK 73104, USA

5Laboratory for Genomics and Bioinformatics, University of Oklahoma Health Sciences Center, 1100 North Lindsay, Oklahoma City, OK 73104, USA

author email corresponding author email

BMC Genomics 2008, 9:213doi:10.1186/1471-2164-9-213

Published: 9 May 2008

Additional files

Additional file 1:

2D Gel Analysis. Virtual 2D gel analysis. Protein migration patterns for select HAdV proteins by virtual 2D gel. Each spot represents a given serotype's homologue based on its predicted amino acid sequence. A. DNA binding protein, B. Viral polymerase, C. Penton base, D. Hexon, E. Protease, and F. pVIII. One protein from HAdV-37 and a homologue from a representative serotype of all 6 HAdV species are represented in each gel.

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