Correlation between NXScores and experimentally verified nucleosome exclusion regions. (a) The -1500 to +500 promoter region of the human genes FOS and CBLL1 are shown with the nucleosome positions from Ozsolak et al. (2007) denoted by black bars superimposed on the NXSensor graphics. The results and correlations of several other genes can be found in Additional file 3. (b) The promoter regions of the yeast benchmark genes CHA1 and HIS3 are shown with the nucleosome positions from Lee et al. (2007) denoted by black bars as above. The NXScore results were uploaded as a Custom Track on the UCSC Genome Browser, and a snapshot was taken with the human RefSeq genes track (a), or the protein coding genes track from yeast (b). (c) The correlation between the mean NXScores for the TSS-200 to TSS+200 promoter region of 19055 genes, and the calculated average log2(Cy5 = Cy3) data of 57 MITF-bound promoters in the human genome.
Radwan et al. BMC Genomics 2008 9:186 doi:10.1186/1471-2164-9-186