Analysis of Aspergillus nidulans metabolism at the genome-scale

Helga David^*¹ , İlknur Ş Özçelik^*² , Gerald Hofmann³ and Jens Nielsen⁴

¹Fluxome Sciences A/S, Diplomvej 378, Kgs. 2800 Lyngby, Denmark

²TÜBİTAK – The Scientific and Technological Research Council of Turkey, Tunus Caddesi No: 80 06100 Kavaklýdere, Ankara, Turkey

³Novozymes A/S, Fermentation Optimization, Hallas Alle 1, Building BD3.44, DK-4400, Kalundborg, Denmark

⁴Center for Microbial Biotechnology, BioCentrum-DTU, Building 223, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark

author email corresponding author email* Contributed equally

BMC Genomics 2008, 9:163doi:10.1186/1471-2164-9-163


Published:	11 April 2008

Additional files

Additional file 1:

List of the reactions comprising the metabolic model developed for A. nidulans. List of the reactions comprising the metabolic model developed for A. nidulans. Each reaction is associated to an ORF within the genome of A. nidulans (when available), and to the EC number of the corresponding enzyme (when available). The classification of the ORFs into categories is also presented. The functional assignments were based on a cut-off in the E-values of BLAST searches of 1E-50. The reactions that are common to the metabolic networks of A. nidulans and S. cerevisiae are represented by AN and SC, respectively.

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Additional file 2:

List of metabolites (abbreviations and full names) included in the metabolic model for A. nidulans. In the abbreviations, the suffixes 'm', 'g', 'e' stand for metabolites localized in the mitochondria, glyoxysomes and extracellular medium, respectively. No suffix was added to cytosolic metabolites.

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Additional file 3:

List of the ORFs associated to each biochemical reaction for different cut-off values in the E-value of BLASTP searches

Format: XLS Size: 99KB Download file

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