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Open AccessResearch article

Impaired barrier function by dietary fructo-oligosaccharides (FOS) in rats is accompanied by increased colonic mitochondrial gene expression

Wendy Rodenburg1,2,3 email, Jaap Keijer1,2 email, Evelien Kramer1,2 email, Carolien Vink1,3 email, Roelof van der Meer3,4 email and Ingeborg MJ Bovee-Oudenhoven1,3 email

1TI Food and Nutrition, Wageningen, The Netherlands

2RIKILT – Institute of Food Safety, Wageningen, The Netherlands

3NIZO Food Research, Ede, The Netherlands

4Nutrigenomics Consortium, TI Food and Nutrition, Wageningen, The Netherlands

author email corresponding author email

BMC Genomics 2008, 9:144doi:10.1186/1471-2164-9-144

Published: 27 March 2008

Additional files

Additional file 1:

Barrier associated genes. The effect of FOS on the expression of potential barrier associated genes.

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Additional file 2:

Functional classification of FOS affected genes by Metacore. Classification of the genes affected by FOS into biological processes analyzed by Metacore.

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Additional file 3:

Genesets enriched in FOS versus control dataset according to GSEA analysis. Classification of the genes affected by FOS into biological processes analyzed by GSEA.

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Additional file 4:

FOS affected genes: Biological processes. Genes affected by FOS and part of a significant biological process.

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Additional file 5:

FOS affected genes: Miscellaneous. Genes affected by FOS but not part of a significantly regulated biological process or genes with unknown function.

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Additional file 6:

Primer sequences. Sequences of the primers used for Q-PCR analysis.

Format: DOC Size: 41KB Download file

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