Phylogenetic analysis of the BPI-like genes: A consensus Maximum-Likelihood tree was generated using the PHYML program after aligning the nucleotide sequences from the N-terminal domain of the two-domain and the full length sequences of the single-domain BPI-like proteins. The values associated with the branch nodes indicate the level of support derived from bootstrap analysis of 1000 replicates. The bar indicates 10 nucleotide substitutions per 100 sequence positions. The sequences used were from human (HS), mouse (MM) or cattle (BT) (see Table 1, Additional file 1 and Additional file 2).
Wheeler et al. BMC Genomics 2007 8:75 doi:10.1186/1471-2164-8-75