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Open AccessResearch article

Single nucleotide polymorphisms (SNPs) are highly conserved in rhesus (Macaca mulatta) and cynomolgus (Macaca fascicularis) macaques

Summer L Street1,2 email, Randall C Kyes2,3 email, Richard Grant4 email and Betsy Ferguson1,2 email

1Genetics Research and Informatics Program, Oregon National Primate Research Center, Oregon Health & Sciences University, Beaverton, OR 97006, USA

2Washington National Primate Research Center, University of Washington, Seattle, WA 98195, USA

3Department of Psychology, University of Washington, Seattle, WA 98195, USA

4SNBL USA, Ltd., Everett, WA 98203, USA

author email corresponding author email

BMC Genomics 2007, 8:480doi:10.1186/1471-2164-8-480

Published: 31 December 2007

Additional files

Additional file 1:

SNP identity and NCBI accession numbers. This file lists the SNPs identified in this study and the associated gene. The NCBI STS (reference sequence) accession numbers for each are shown.

Format: PDF Size: 12KB Download file

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Additional file 2:

SNPs identified through sequencing in 10 genomic regions of M. fascicularis and M. mulatto. All SNPs identified in 10 genomic regions by sequencing of 20 M. fascicularis and 20 M. mulatta are shown at the top. Loci highlighted in green showed no variant allele in that population; yellow highlight indicates a SNP was detected, and red indicates that only the minor allele of the SNP variant was detected in the population.

Format: PDF Size: 14KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional file 3:

SNP assay gene summary. The fifty-three genes represented in the SNP genotype assay are listed, along with chromosome location. Those genes that were also analyzed by direct sequencing are noted.

Format: PDF Size: 8KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional file 4:

Sequence information for M. fascicularis. The primer information and reference sequences for the ten gene regions sequenced in M. fascicularis are listed.

Format: PDF Size: 8KB Download file

This file can be viewed with: Adobe Acrobat Reader


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