Figure 4.

FOSB Identification and Immunohistochemistry. A) Ranking, association scores, and confidence calls for pathway terms associated with the 100 genes with increased expression in metastatic prostate tumors compared to local prostate tumors (Association score is the log of the product of frequency (logPF)). B) Two examples of local (left) and metastatic (right) prostate cancer FOSB expression measured by immunohistochemistry. C) Percentage of epithelial cell nuclei staining positive for benign prostate epithelium (n = 14), local prostate cancer (n = 20), and metastatic prostate cancer (n = 22) (* Met v. Local, p = 0.0013).