Figure 1.

HL60 Leukemia cells treated with ATRA. A) May Grunwald Giemsa stain of HL60 cells prior to (upper) and following treatment with ATRA (lower). B) Heat map of the top 100 genes with increased expression in HL60 cells treated with ATRA compared to untreated HL60 cells (Red – high normalized expression, Blue – low normalized expression). C) Percentage of cells positive for nitro blue tetrazolium (NBT) reduction (Mean +/- St dev). D) Literature Lab ranking, association scores, and confidence calls for cell physiology, metabolism, and pathway terms (Association score is the log of the product of frequency (logPF)).