Table 1

Discriminatory key to classify indecisive isoforms.

Characteristics
FeSOD
MnSOD

Metal specificity
Fe
Mn
Amino acid length
199–229
200–316
Theoretical molecular weight
21–25 KDa
22–34 KDa
No. of a helix*
13
14
No. of b strand*
3
3
Domains
N & C terminal
N & C terminal
Motif
DVWEHAYY
DVWEHAYY
Active site residues*
Fig 3
Fig 4
Structurally highly conserved metal specific residues
F184XXXA188Q189.......T280......F/Y303
R184XXXG188G189.......G280......W303
Conserved residue with photosynthetic role
K87, K139
None
Transmembrane hydrophobic pocket
Absent
Present

* – Based on the structural analysis of MnSOD of Anabaena sp. (PDB No: 1gv3) and FeSOD of Thermosynechococcus elongatus BP-1 (PDB No: 1my6)

Priya et al. BMC Genomics 2007 8:435   doi:10.1186/1471-2164-8-435