SNP analysis workflow. The DNA sequence output was analyzed using PolyPhred software to identify SNPs and to report the relative quality score of the SNP calls. SNPs with low quality scores or with inconsistent reports were reviewed manually. The approved SNP data was deposited into a local database for population, frequency and genotype analysis. Based upon the statistical results, some SNPs were selected for inclusion in Sequenom iPlex SNP panel.
Ferguson et al. BMC Genomics 2007 8:43 doi:10.1186/1471-2164-8-43