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Open AccessMethodology article

Computational selection and prioritization of candidate genes for Fetal Alcohol Syndrome

Zané Lombard1 email, Nicki Tiffin2,3 email, Oliver Hofmann2 email, Vladimir B Bajic2 email, Winston Hide2 email and Michèle Ramsay1 email

1Division of Human Genetics, National Health Laboratory Service & School of Pathology, University of the Witwatersrand, Johannesburg, 2001, South Africa

2South African National Bioinformatics Institute (SANBI) Research Group, University of the Western Cape, Bellville, 7530, South Africa

3Division of Human Genetics, University of Cape Town, Cape Town, 8001, South Africa

author email corresponding author email

BMC Genomics 2007, 8:389doi:10.1186/1471-2164-8-389

Published: 25 October 2007

Additional files

Additional file 1:

The 87 top-ranked genes for FAS identified using binary matrix filtering

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Additional file 2:

GO term annotations significantly over-represented among the top-ranked genes. The table provided represent the GO biological process, cellular component and molecular function terms over-represented among the top-ranked genes

Format: PDF Size: 60KB Download file

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Additional file 3:

Promoter element binding site analysis. The tables provided represent the promoter elements that have been found in the target promoter set relative to the background promoter set (Table 1) and the pairs of promoter elements at maximum mutual distance of 50 nucleotides (Table 2) that have been found in the target promoter set relative to the background promoter set.

Format: PDF Size: 74KB Download file

This file can be viewed with: Adobe Acrobat Reader


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