Normalization of array-CGH data: influence of copy number imbalances
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* Corresponding authors: Johan Staaf johan.staaf@med.lu.se - Johan Vallon-Christersson johan.vallon-christersson@med.lu.se
BMC Genomics 2007, 8:382 doi:10.1186/1471-2164-8-382
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BioMed Central: 10 citations
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Method
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Research article
Göran Jönsson, Johan Staaf, Johan Vallon-Christersson, Markus Ringnér, Karolina Holm, Cecilia Hegardt, Haukur Gunnarsson, Rainer Fagerholm, Carina Strand, Bjarni A Agnarsson, Outi Kilpivaara, Lena Luts, Päivi Heikkilä, Kristiina Aittomäki, Carl Blomqvist, Niklas Loman, Per Malmström, Håkan Olsson, Oskar Th Johannsson, Adalgeir Arason, Heli Nevanlinna, Rosa B Barkardottir, Åke Borg Breast Cancer Research 2010, 12:R42 (24 June 2010) The identification of six subtypes of breast cancer - differing in biology, genomic alterations and patient outcome - may prove useful for understanding tumor development and for prognostic and treatment prediction purposes.
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Research article
Johan Staaf, Göran Jönsson, Markus Ringnér, Johan Vallon-Christersson, Dorthe Grabau, Adalgeir Arason, Haukur Gunnarsson, Bjarni A Agnarsson, Per-Olof Malmström, Oskar Johannsson, Niklas Loman, Rosa B Barkardottir, Åke Borg Breast Cancer Research 2010, 12:R25 (6 May 2010) A survey of copy number alterations in HER2+ breast tumors using a combination of array comparative genomic hybridization and gene expression analyses pinpoints significant genomic aberrations, including potentially novel therapeutic targets.
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Potential predictive markers of chemotherapy resistance in stage III ovarian serous carcinomas Lovisa Österberg, Kristina Levan, Karolina Partheen, Ulla Delle, Björn Olsson, Karin Sundfeldt, György Horvath BMC Cancer 2009, 9:368 (18 October 2009) |
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Bart PP van Houte, Thomas W Binsl, Hannes Hettling, Walter Pirovano, Jaap Heringa BMC Genomics 2009, 10:401 (26 August 2009) |
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Methodology article
Improved analysis of bacterial CGH data beyond the log-ratio paradigm Lars Snipen, Otto L Nyquist, Margrete Solheim, Ågot Aakra, Ingolf F Nes BMC Bioinformatics 2009, 10:91 (19 March 2009) |
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Research
Tomasz Gambin, Krzysztof Walczak BMC Bioinformatics 2009, 10(Suppl 1):S64 (30 January 2009) |
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Methodology article
Johan Staaf, Johan Vallon-Christersson, David Lindgren, Gunnar Juliusson, Richard Rosenquist, Mattias Höglund, Åke Borg, Markus Ringnér BMC Bioinformatics 2008, 9:409 (2 October 2008) |
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Method
Johan Staaf, David Lindgren, Johan Vallon-Christersson, Anders Isaksson, Hanna Göransson, Gunnar Juliusson, Richard Rosenquist, Mattias Höglund, Åke Borg, Markus Ringnér Genome Biology 2008, 9:R136 (16 September 2008) A strategy is presented for detection of loss-of-heterozygosity and allelic imbalance in cancer cells from whole genome SNP genotyping data. |