Fasting induces a biphasic adaptive metabolic response in murine small intestine

doi:10.1186/1471-2164-8-361

BMC Genomics

Volume 8

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Sokolović M
Wehkamp D
Sokolović A
Vermeulen J
Gilhuijs-Pederson LA
van Haaften RI
Nikolsky Y
Evelo CT
van Kampen AH
Hakvoort TB
Lamers WH

on PubMed

Sokolović M
Wehkamp D
Sokolović A
Vermeulen J
Gilhuijs-Pederson LA
van Haaften RI
Nikolsky Y
Evelo CT
van Kampen AH
Hakvoort TB
Lamers WH
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Research article

Fasting induces a biphasic adaptive metabolic response in murine small intestine

Milka Sokolović¹ , Diederik Wehkamp² , Aleksandar Sokolović¹ , Jacqueline Vermeulen¹ , Lisa A Gilhuijs-Pederson² , Rachel IM van Haaften³ , Yuri Nikolsky⁴ , Chris TA Evelo³ , Antoine HC van Kampen² , Theodorus BM Hakvoort¹ and Wouter H Lamers¹

¹AMC Liver Centre, Academic Medical Centre, Amsterdam, The Netherlands

²Bioinformatics Laboratory, Academic Medical Centre, Amsterdam, The Netherlands

³BiGCaT Bioinformatics, University of Maastricht, Maastricht, The Netherlands

⁴GeneGo, Inc., St. Joseph, MI, USA

author email corresponding author email

BMC Genomics 2007, 8:361doi:10.1186/1471-2164-8-361


Published:	9 October 2007

Additional files

Additional file 1:

Fold changes in response to fasting. The file provided contains lists of all the genes significantly regulated (≥ 1.4 fold) per time point of fasting.

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Additional file 2:

Supplementary tables 1–3 Supplementary table 1 contains gene-specific primer sequences, product lengths, annealing temperatures, and MgCl₂concentrations. Supplementary table 2 contains a selection of genes with an expression pattern unique for a certain phase of fasting. Supplementary table 3 contains PPARα target genes differentially expressed in fasted intestine.

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Additional file 3:

Pathway specific gene lists. The file contains lists of the genes significantly regulated in the pathways shown in the Figures 6–10. The data discussed in this publication have been deposited in NCBIs Gene Expression Omnibus (GEO, [74]) and are accessible through GEO Series accession number GSE8019.

Format: XLS Size: 46KB Download file

This file can be viewed with: Microsoft Excel Viewer