|
Cross-validation of two independent datasets |
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| Profile |
Validated by |
Accuracy |
AUC |
Odds ratio |
|
|
||||
| Rosetta |
Stanford |
74.2% |
0.808 |
9.06 |
| Stanford |
Rosetta |
70.7% |
0.786 |
6.68 |
| Overall |
72.2% |
0.795 |
6.71 |
|
|
SEP scores of validating patients were calculated with the 60-gene profile of the validated dataset. Patients were evenly classified into two groups using median score as threshold. Accuracy: percentage of correctly classified patients; AUC: area of SEP-based ROC curve; Odds ratio: the association between SEP and disease outcome based on Fisher's exact test. | ||||
Zhang et al. BMC Genomics 2007 8:331 doi:10.1186/1471-2164-8-331 |
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