BMC Genomics

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Glycerate kinase of the hyperthermophilic archaeon Thermoproteus tenax: new insights into the phylogenetic distribution and physiological role of members of the three different glycerate kinase classes

Daniel Kehrer, Hatim Ahmed, Henner Brinkmann and Bettina Siebers*

BMC Genomics 2007, 8:301 doi:10.1186/1471-2164-8-301

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Non-homologous isofunctional enzymes: A systematic analysis of alternative solutions in enzyme evolution

Marina V Omelchenko, Michael Y Galperin, Yuri I Wolf, Eugene V Koonin Biology Direct 2010, 5:31 (30 April 2010)

Almost 10% of the biochemical reactions in the Enzyme Commission nomenclature are catalyzed by two or more enzymes with different structural folds and hence independent evolutionary origins.

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Complete genome sequence of the extremely acidophilic methanotroph isolate V4, Methylacidiphilum infernorum, a representative of the bacterial phylum Verrucomicrobia

Shaobin Hou, Kira S Makarova, Jimmy HW Saw, Pavel Senin, Benjamin V Ly, Zhemin Zhou, Yan Ren, Jianmei Wang, Michael Y Galperin, Marina V Omelchenko, Yuri I Wolf, Natalya Yutin, Eugene V Koonin, Matthew B Stott, Bruce W Mountain, Michelle A Crowe, Angela V Smirnova, Peter F Dunfield, Lu Feng, Lei Wang, Maqsudul Alam Biology Direct 2008, 3:26 (1 July 2008)

Genome sequence of a methanotrophic member of the bacterial phylum Verrucomicrobia reveals adaptations to the methane utilization under acidic conditions and supports grouping Planctomycetes, Verrucomicrobia and Chlamydiae into a superphylum

Research   Open Access

Computational identification of obligatorily autocatalytic replicators embedded in metabolic networks

Ádám Kun, Balázs Papp, Eörs Szathmáry Genome Biology 2008, 9:R51 (10 March 2008)

Small-molecular metabolic autocatalytic regulators, which are crucial to metabolic pathways, are identified in a novel systems-wide study in different organisms, revealing that in the enzymatic reactions of conserved autocatalytic cycles, the autocatalytic behavior of replicators varies.