Table 2 |
|||
|
Genes that are differentially expressed in mesenteric white adipose tissue of OE-treated rats |
|||
|
Ratio |
GeneBank |
Functional Classification |
|
|
|
|||
|
Down-regulated genes |
|||
|
|
|||
|
Fatty acid synthase (FAS) |
0.11 |
Metabolism of cofactors, vitamins & related substances |
|
|
Acetyl-CoA carboxylase (ACC) |
0.19 |
Simple Lipid metabolism |
|
|
Prostaglandin d2 receptor |
0.30 |
Hormone Receptors |
|
|
Fatty acid transport protein (FATP1) |
0.31 |
Other membrane channels & Transporters |
|
|
Very long chain acyl-coa dehydrogenase (vlcad) |
0.32 |
Metabolism of Cofactors, Vitamins & Related Substances |
|
|
Lipoprotein lipase (LPL) |
0.33 |
Complex Lipid Metabolism |
|
|
Slow voltage-gated potassium channel protein |
0.33 |
Voltage-gated ion channels |
|
|
Low density lipoprotein receptor |
0.35 |
Other receptors |
|
|
Pyruvate dehydrogenase kinase kinase |
0.37 |
Intracellular kinase network members |
|
|
Adipocyte fatty acid-binding protein (FABP4) |
0.38 |
Other Trafficking & Targeting proteins |
|
|
Carnitine palmitoyltransferase 1b (CPT1b) |
0.39 |
Simple Lipid metabolism |
|
|
Hormone-sensitive lipase (HSL) |
0.40 |
Simple Lipid Metabolism |
|
|
Cytochrome P450 2c7 |
0.42 |
Complex Lipid Metabolism |
|
|
Glucose-6-P-dehydrogenase |
0.45 |
Complex Carbohydrate Metabolism |
|
|
Retinoid X receptor beta |
0.45 |
Nuclear receptors |
|
|
Brain fatty acid binding protein |
0.45 |
Other Trafficking & Targeting proteins |
|
|
Adenyl cyclase |
0.46 |
Adenylate/Guanylate Cyclases & Diesterases |
|
|
Proteasome 26s subunit 2 |
0.47 |
Proteosomal Proteins |
|
|
|
|||
|
Up-regulated genes |
|||
|
|
|||
|
Insulin receptor-related receptor alpha subunit |
1.52 |
Intracellular Kinase network members |
|
|
Cytochrome p450 4f5 |
1.72 |
Complex Lipid Metabolism |
|
|
Tumor necrosis factor alpha (TNFα) |
1.77 |
Growth Factors, Cytokines hemokines |
|
|
GTP-binding protein |
1.82 |
G Proteins |
|
|
Ras-gtpase activation protein |
1.85 |
GTP/GDP exchangers & GTPse activity modulators |
|
|
Cytochrome p450 4b1 |
2.01 |
Other Metabolism Enzymes |
|
|
Protein arginine n-methyltransferase 1 |
3.59 |
Intracellular Adaptors eceptor Associated Proteins |
|
|
|
|||
|
The expression of each gene is reported as the ratio of the value obtained after each treatment relative to control after normalization of the data. |
|||
|
Salas et al. BMC Genomics 2007 8:292 doi:10.1186/1471-2164-8-292 |
|||
