|
Genes that are differentially expressed in mesenteric white adipose tissue of OE-treated rats |
|||
| Ratio |
GeneBank |
Functional Classification |
|
|
|
|||
| Down-regulated genes |
|||
|
|
|||
| Fatty acid synthase (FAS) |
0.11 |
M76767 |
Metabolism of cofactors, vitamins & related substances |
| Acetyl-CoA carboxylase (ACC) |
0.19 |
J03808 |
Simple Lipid metabolism |
| Prostaglandin d2 receptor |
0.30 |
U92289 |
Hormone Receptors |
| Fatty acid transport protein (FATP1) |
0.31 |
U89529 |
Other membrane channels & Transporters |
| Very long chain acyl-coa dehydrogenase (vlcad) |
0.32 |
D30647 |
Metabolism of Cofactors, Vitamins & Related Substances |
| Lipoprotein lipase (LPL) |
0.33 |
L03294 |
Complex Lipid Metabolism |
| Slow voltage-gated potassium channel protein |
0.33 |
M22412 |
Voltage-gated ion channels |
| Low density lipoprotein receptor |
0.35 |
X13722 |
Other receptors |
| Pyruvate dehydrogenase kinase kinase |
0.37 |
L22294 |
Intracellular kinase network members |
| Adipocyte fatty acid-binding protein (FABP4) |
0.38 |
U75581 |
Other Trafficking & Targeting proteins |
| Carnitine palmitoyltransferase 1b (CPT1b) |
0.39 |
D43632 |
Simple Lipid metabolism |
| Hormone-sensitive lipase (HSL) |
0.40 |
U40001 |
Simple Lipid Metabolism |
| Cytochrome P450 2c7 |
0.42 |
M18335 |
Complex Lipid Metabolism |
| Glucose-6-P-dehydrogenase |
0.45 |
X07467 |
Complex Carbohydrate Metabolism |
| Retinoid X receptor beta |
0.45 |
M81766 |
Nuclear receptors |
| Brain fatty acid binding protein |
0.45 |
U02096 |
Other Trafficking & Targeting proteins |
| Adenyl cyclase |
0.46 |
M80633 |
Adenylate/Guanylate Cyclases & Diesterases |
| Proteasome 26s subunit 2 |
0.47 |
D50694 |
Proteosomal Proteins |
|
|
|||
| Up-regulated genes |
|||
|
|
|||
| Insulin receptor-related receptor alpha subunit |
1.52 |
M90661 |
Intracellular Kinase network members |
| Cytochrome p450 4f5 |
1.72 |
U39207 |
Complex Lipid Metabolism |
| Tumor necrosis factor alpha (TNFα) |
1.77 |
X66539 |
Growth Factors, Cytokines hemokines |
| GTP-binding protein |
1.82 |
L19699 |
G Proteins |
| Ras-gtpase activation protein |
1.85 |
L13151 |
GTP/GDP exchangers & GTPse activity modulators |
| Cytochrome p450 4b1 |
2.01 |
M29853 |
Other Metabolism Enzymes |
| Protein arginine n-methyltransferase 1 |
3.59 |
U60882 |
Intracellular Adaptors eceptor Associated Proteins |
|
The expression of each gene is reported as the ratio of the value obtained after each treatment relative to control after normalization of the data. | |||
Salas et al. BMC Genomics 2007 8:292 doi:10.1186/1471-2164-8-292 |
|||