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Weight change, food intake and plasma parameters of Wistar rats at 48-hours after the onset of an oral treatment with oleoyl-estrone (OE) |
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| Parameter |
Group |
Mean ± SEM |
|
|
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| Body weight (% of initial) |
Control |
101 ± 0.89 |
| OE |
96.8 ± 0.76 * |
|
| Cumulative food intake (g) |
Control |
42.9 ± 2.11 |
| OE |
29.7 ± 2.61 * |
|
| Glucose (mM) |
Control |
7.72 ± 0.20 |
| OE |
7.65 ± 0.31 |
|
| Total Cholesterol (mM) |
Control |
1.48 ± 0.13 |
| OE |
0.88 ± 0.04 * |
|
| HDL-cholesterol (mM) |
Control |
0.98 ± 0.14 |
| OE |
0.22 ± 0.02 * |
|
| HDL/total cholesterol ratio (%) |
Control |
66.2 ± 7.21 |
| OE |
23.7 ± 2.05 * |
|
| Non-esterified fatty acids (mM) |
Control |
0.56 ± 0.08 |
| OE |
0.60 ± 0.04 |
|
| 3-hydroxybutyrate (mM) |
Control |
0.28 ± 0.02 |
| OE |
0.30 ± 0.06 |
|
| Triacylglycerols (mM) |
Control |
0.91 ± 0.09 |
| OE |
0.79 ± 0.10 |
|
|
The data are the mean ± SEM of data from six animals per group. Statistical comparison between groups was determined using the Student's t test. * = P < 0.05 | ||
Salas et al. BMC Genomics 2007 8:292 doi:10.1186/1471-2164-8-292 |
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