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Open AccessResearch article

Microarray amplification bias: loss of 30% differentially expressed genes due to long probe – poly(A)-tail distances

Mirjam C Boelens1,2 email, Gerard J te Meerman3 email, Johan H Gibcus1 email, Tjasso Blokzijl1 email, H Marike Boezen4 email, Wim Timens1 email, Dirkje S Postma2 email, Harry JM Groen2 email and Anke van den Berg1 email

Department of Pathology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

Pulmonology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

author email corresponding author email

BMC Genomics 2007, 8:277doi:10.1186/1471-2164-8-277

Published: 15 August 2007

Additional files

Additional file 1:

Probe – poly(A)-tail distances of Agilent whole human genome array. For 22,388 probes of the Agilent WHG array, the determined probe – poly(A)-tail distances are listed in this table.

Format: XLS Size: 2.3MB Download file

This file can be viewed with: Microsoft Excel Viewer


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