Open Access Research article

Insight into transcription factor gene duplication from Caenorhabditis elegans Promoterome-driven expression patterns

John S Reece-Hoyes1, Jane Shingles1, Denis Dupuy2, Christian A Grove3, Albertha JM Walhout3, Marc Vidal2 and Ian A Hope1*

1 Institute of Integrative and Comparative Biology, Faculty of Biological Sciences, University of Leeds, Clarendon Way, Leeds, LS2 9JT, West Yorkshire, UK

2 Center for Cancer Systems Biology (CCSB), and Department of Cancer Biology, Dana-Farber Cancer Institute and Department of Genetics, Harvard Medical School, 44 Binney Street, Boston, Massachusetts 02115, USA

3 Program in Gene Function and Expression and Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, 364 Plantation Street, Lazare Research Building, Room 605, MA 01605, USA

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BMC Genomics 2007, 8:27 doi:10.1186/1471-2164-8-27

Published: 23 January 2007

Additional files

Additional File 1:

contains descriptions of GFP expression patterns, in terms of tissue type and life stage, as driven by Promoterome inserts for the 366 transcription factor genes assayed.

Format: XLS Size: 116KB Download file

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Additional File 2:

contains a summary of comparisons between Promoterome driven reporter gene expression patterns and expression patterns generated previously by immunomicroscopy or in situ hybridization for the 40 C. elegans genes for which such comparison can be made.

Format: XLS Size: 51KB Download file

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Additional File 3:

contains a list of the 934 putative transcription factor genes, wTF2.0, with their C. briggsae orthologue where an orthologue could be identified.

Format: XLS Size: 115KB Download file

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Open Data