Table 4

Comparison of expression ratios in patients with SALS and Alzheimer's disease

Expression Ratios

Gene Symbol

UniGene ID

SALS

AD

Comparison


AQP1

Hs.76152

2.52

1.62

=

CEBPD

Hs.440829

2.52

1.77

==

SERPINA3

Hs.534293

2.38

2.40

==

SLC14A1

Hs.101307

2.15

2.20

==


SLC12A5

Hs.21413

0.50

0.40

==

CYCS

Hs.437060

0.49

0.52

==

DSCR1L1

Hs.440168

0.49

0.39

==

NRGN

Hs.524116

0.49

0.41

==

PCP4

Hs.80296

0.49

0.32

=

ATP5A1

Hs.298280

0.48

0.61

==

CAP2

Hs.132902

0.48

0.52

==

GNAS

Hs.125898

0.48

0.48

==

NDUFA4

Hs.50098

0.48

0.62

==

UCHL1

Hs.518731

0.48

0.67

==

YWHAH

Hs.226755

0.48

0.53

==

PNMA2

Hs.521466

0.46

0.56

==

RTN1

Hs.368626

0.46

0.37

==

OLFM1

Hs.522484

0.43

0.55

==

RTN4

Hs.429581

0.43

0.75

=

CHN1

Hs.380138

0.42

0.50

==

MDH1

Hs.526521

0.41

0.54

==

BEX1

Hs.334370

0.40

0.63

=

NEF3

Hs.458657

0.38

0.28

==

VSNL1

Hs.444212

0.35

0.26

==

ENC1

Hs.104925

0.34

0.74

=

NEFL

Hs.521461

0.32

0.35

==

SNAP25

Hs.167317

0.31

0.59

=


MT2A

Hs.418241

2.43

1.31

<>

MT1E

Hs.534330

2.29

1.32

<>

MT1G

Hs.433391

2.19

1.36

<>

ANXA2

Hs.511605

2.06

1.45

<>

MT1X

Hs.374950

2.02

1.39

<>

ATP1A3

Hs.515427

0.49

1.46

<>

ATP6V1A

Hs.477155

0.49

0.78

<>

EGR1

Hs.326035

0.46

1.63

<>

EIF4A2

Hs.478553

0.45

0.75

<>

NSF

Hs.431279

0.45

1.01

<>

CHGB

Hs.516874

0.39

2.37

<>


Expression ratios for candidate genes identified in the present report (SALS) are compared to those found for data by Blalock et al. [18] for Alzheimer's disease (AD), giving a correlation coefficient of r = 0.696. AD data were retrieved from GEO (series GSE1297) and processed as described in the Methods section.

== both tissues give the same result, differing ≤1.5-fold

= both tissues give the same result, differing >1.5-fold

<> both tissues give different results (up- vs. down-regulation or deregulation vs. constancy, defining constancy as a ≤1.5-fold deregulation)

Lederer et al. BMC Genomics 2007 8:26   doi:10.1186/1471-2164-8-26

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