Table 3

Comparison of expression ratios in motor cortex and spinal cord

Expression Ratios

Gene Symbol

UniGene ID

Motor Cortex

Spinal Cord

Comparison


AQP1

Hs.76152

2.52

2.84

==

MT2A

Hs.418241

2.43

4.66

=

SLC14A1

Hs.101307

2.15

1.91

==

ANXA2

Hs.511605

2.06

4.49

=

MT1X

Hs.374950

2.02

1.99

==

FCGBP

Hs.111732

2.00

3.14

=


DSCR1L1

Hs.440168

0.49

0.49

==

PCP4

Hs.80296

0.49

0.60

==

SCG5

Hs.156540

0.48

0.58

==

UCHL1

Hs.518731

0.48

0.48

==

GABRA1

Hs.175934

0.47

0.56

==

EGR1

Hs.326035

0.46

0.42

==

OLFM1

Hs.522484

0.43

0.50

==

VSNL1

Hs.444212

0.35

0.38

==


SNAP25

Hs.167317

0.31

0.82

<>

MDH1

Hs.526521

0.41

0.68

<>

CHN1

Hs.380138

0.42

0.71

<>

EIF4A2

Hs.478553

0.45

0.98

<>

RTN1

Hs.368626

0.46

0.71

<>

ATP5A1

Hs.298280

0.48

1.13

<>

NDUFA4

Hs.50098

0.48

0.73

<>

PCSK1

Hs.78977

0.39

1.73

<>

CHGB

Hs.516874

0.39

1.65

<>


Expression ratios for candidate genes identified in the present report (Motor Cortex) are compared to those found by Dangond et al. [4] (Spinal Cord), giving a correlation coefficient of r = 0.85. Spinal cord data were retrieved from the Gene Expression Omnibus Database (GEO, series GSE833) and processed as described in the Methods section.

== both tissues give the same result, differing ≤1.5-fold

= both tissues give the same result, differing >1.5-fold

<> both tissues give different results (up- vs. down-regulation or deregulation vs. constancy, defining constancy as a ≤1.5-fold deregulation)

Lederer et al. BMC Genomics 2007 8:26   doi:10.1186/1471-2164-8-26

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