Coding/peak versus block substitution for V1R paralogs/orthologs. Nucleotide substitution rates within promoters of mouse paralogs (red) and mouse-rat orthologs (blue) relative to substitution rates within non-coding/non-promoter portions of gene blocks is compared to relative substitution rates within paralogous coding regions (green) for various subfamilies. Rat peaks were identified by using BLAST  to identify orthology to mouse peaks. Standard deviations in various pairwise comparisons are shown. Orthologous comparisons within the H and I subfamilies are not possible because there are no intact H and I subfamily members in rat.
Stewart and Lane BMC Genomics 2007 8:253 doi:10.1186/1471-2164-8-253