Figure 3.

Coding/peak versus block substitution for V1R paralogs/orthologs. Nucleotide substitution rates within promoters of mouse paralogs (red) and mouse-rat orthologs (blue) relative to substitution rates within non-coding/non-promoter portions of gene blocks is compared to relative substitution rates within paralogous coding regions (green) for various subfamilies. Rat peaks were identified by using BLAST [40] to identify orthology to mouse peaks. Standard deviations in various pairwise comparisons are shown. Orthologous comparisons within the H and I subfamilies are not possible because there are no intact H and I subfamily members in rat.