Prevalence of the EH1 Groucho interaction motif in the metazoan Fox family of transcriptional regulators

doi:10.1186/1471-2164-8-201

BMC Genomics

Volume 8

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Vekker A
Stayrook S
Lewis M
Kessler DS

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Vekker A
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Lewis M
Kessler DS
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Research article

Prevalence of the EH1 Groucho interaction motif in the metazoan Fox family of transcriptional regulators

Sergey Yaklichkin¹ , Alexander Vekker² , Steven Stayrook³ , Mitchell Lewis³ and Daniel S Kessler¹

¹Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, 1110 Biomedical Research Building II/III, 421 Curie Boulevard, Philadelphia, PA 19104, USA

²Department of Economics, University of Pennsylvania, 328 McNeil Building, 3718 Locust Walk, Philadelphia, PA 19104, USA

³Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, 813B Stellar-Chance Laboratories, 422 Curie Boulevard, Philadelphia, PA 19104, USA

author email corresponding author email

BMC Genomics 2007, 8:201doi:10.1186/1471-2164-8-201


Published:	28 June 2007

Additional files

Additional file 1:

Phylogenetic Tree of the Fox Gene Family Indicating the Occurrence of eh1 Motifs. A phylogenetic tree of the entire Fox gene family indicating which individual proteins contain an eh1-like motif.

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Additional file 2:

Legends for Additional Files 1 and 3. Description of data presented in Additional Files 1 and 3.

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Additional file 3:

The amino acid composition of eh1-like motifs identified in individual Fox protein subclasses. Diagrams representing the amino acid composition of the eh1-like motifs identified in each Fox family subclass of invertebrate and vertebrate organisms.

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Additional file 4:

Propensity for α-helix formation for eh1-like motifs in selected Fox proteins. An analysis of the propensity for α-helix formation at the position of individual residues within the eh1-like motifs of selected Fox family proteins.

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