Research article
Rapid evolution of cancer/testis genes on the X chromosome
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* Corresponding author: Brian J Stevenson brian.stevenson@licr.org
1 Ludwig Institute for Cancer Research and Swiss Institute of Bioinformatics, CH-1015 Lausanne, Switzerland
2 South African National Bioinformatics Institute, University of the Western Cape, Bellville, 7535, South Africa
3 Ludwig Institute for Cancer Research, New York Branch at Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA
BMC Genomics 2007, 8:129 doi:10.1186/1471-2164-8-129
Published: 23 May 2007Additional files
Additional File 1:
Homology data on the human:chimpanzee putative orthologues used in this study. Excel spreadsheet presenting homology data on the human:chimpanzee putative orthologues.
Format: XLS Size: 87KB Download file
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Additional File 2:
Phylogenetic analysis of CT and control gene ORFs using codeml. Excel spreadsheet presenting data additional to that displayed in Table 2.
Format: XLS Size: 63KB Download file
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Additional File 3:
Significance of the differences in the distributions of dN/dS ratios between CT and control ORFs using a parametric t-test. Distribution of dN/dS ratios assessed by parametric t-test. The results are qualitatively similar to those presented in Table 3 and confirm that the distribution of dN/dS values is different between CT genes and controls.
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