Research article
CAG-encoded polyglutamine length polymorphism in the human genome
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* Corresponding author: BF Francis Ouellette francis@bioinformatics.ubc.ca
- † Equal contributors
1 UBC Bioinformatics Centre, Michael Smith Laboratories, University of British Columbia, Vancouver, Canada
2 Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, Canada
3 Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, Canada
4 Department of Medical Genetics, University of British Columbia, Vancouver, Canada
5 Department of Psychiatry, University of British Columbia, Vancouver, Canada
BMC Genomics 2007, 8:126 doi:10.1186/1471-2164-8-126
Published: 22 May 2007Additional files
Additional file 1:
Ethnic composition of control population.
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Additional file 2:
Allele length distributions in a normal population for 64 polyglutamine-encoding CAG trinucleotide repeat targets (A) – (BL). This multi-page document provides plots of allele frequency distributions.
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Additional file 3:
Genes in over-represented GO terms under Biological Process. For each over-represented GO term and its GO ID, this document lists the CAGpolyQ repeat-containing genes that were annotated with that GO term.
Format: PDF Size: 8KB Download file
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Additional file 4:
Genes in over-represented GO terms under Molecular Function. For each over-represented GO term and its GO ID, this document lists the CAGpolyQ repeat-containing genes that were annotated with that GO term.
Format: PDF Size: 8KB Download file
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Additional file 5:
Genes in over-represented GO terms under Cellular Component. For each over-represented GO term and its GO ID, this document lists the CAGpolyQ repeat-containing genes that were annotated with that GO term.
Format: PDF Size: 8KB Download file
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Additional file 6:
Genes and their shared GO terms under Cellular Component. This document provides GO IDs, their descriptions, and the lists of CAGpolyQ repeat-containing genes that shared these annotations above the 99th percentile cutoff.
Format: PDF Size: 7KB Download file
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Additional file 7:
Genes and their shared GO terms under Biological Process. This document provides GO IDs, their descriptions, and the lists of CAGpolyQ repeat-containing genes that shared these annotations above the 99th percentile cutoff.
Format: PDF Size: 9KB Download file
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Additional file 8:
Genes and their shared GO terms under Molecular Function. This document provides GO IDs, their descriptions, and the lists of CAGpolyQ repeat-containing genes that shared these annotations above the 99th percentile cutoff.
Format: PDF Size: 8KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional file 9:
Conditions for PCR amplification of CAGpolyQ repeats in 64 CAGpolyQ repeats. This table provides primer sequences, annealing temperatures and expected fragment sizes for screening these repeats.
Format: XLS Size: 26KB Download file
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