Additional file 1.

Example of printing defect in glass oligonucleotide arrays. Example of printing defects associated with glass long oligonucleotide arrays juxtaposed with well defined spots from one region of the microarray. These defects are characteristic of spot overprinting and have a clear impact on array to array variability. Spots that are obviously defective were removed prior to array quantitation.

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Tsai et al. BMC Genomics 2006 7:328   doi:10.1186/1471-2164-7-328