BMC Genomics

official impact factor 4.21

Open Access Research article

Linkage disequilibrium of evolutionarily conserved regions in the human genome

Mamoru Kato1, Akihiro Sekine1, Yozo Ohnishi1, Todd A Johnson1, Toshihiro Tanaka1, Yusuke Nakamura1,2 and Tatsuhiko Tsunoda1*

Author Affiliations

1 SNP Research Center, RIKEN, Yokohama, Japan

2 Human Genome Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan

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BMC Genomics 2006, 7:326 doi:10.1186/1471-2164-7-326

Published: 28 December 2006

Additional files

Additional File 1:

A figure showing plots of the moving average of the fraction of complete or nearly complete LD (r2 > 0.8) versus distance between SNPs for all four populations.

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Open Data

Additional File 2:

A table showing the regression coefficients, ratios of base pairs in conserved regions to non-conserved regions, and base-pair fractions in the genome for sequence features.

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Open Data

Additional File 3:

A table showing the results of partial correlation analysis to detect sequence features that involve weaker LD in conserved regions.

Format: DOC Size: 44KB Download file

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Open Data