A dense network of molecular interactions containing differentially expressed Core genes in colon cancer. Over- or under-expressed genes, respectively, are indicated by a blue or red disk above-right of the gene-product icon. Green or red lines represent stimulatory or inhibitory interactions, respectively. Many transcription factors (e.g., p53) and signaling kinases (e.g., ERK1) are excluded due to their multiplicity of connections. The general partitioning of the nodes into canonical pathways are shown as bold text.
Gardina et al. BMC Genomics 2006 7:325 doi:10.1186/1471-2164-7-325