Table 4 |
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|
Frequency decrease of G:C→A:T after removal of CpG→TpG/CpA SNPs |
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|
Category |
GC content (%) |
Frequency decrease of G:C→A:T (%) |
|
|
|
|||
|
Un-normalized |
Normalized |
||
|
|
|||
|
Genome |
40.0 |
8.8 |
9.7 |
|
Intergenic regions |
39.4 |
8.2 |
9.2 |
|
Genes |
41.0 |
9.7 |
10.4 |
|
Introns |
39.7 |
8.8 |
9.7 |
|
Exons |
51.7 |
19.4 |
19.2 |
|
CpG islands |
62.0 |
12.1 |
11.2 |
|
Intergenic regions |
<35 (31.4a) |
5.7 |
7.1 |
|
35–40 (37.3) |
7.2 |
8.1 |
|
|
40–45 (42.2) |
9.0 |
9.6 |
|
|
45–50 (47.2) |
11.1 |
11.3 |
|
|
50–55 (52.2) |
13.0 |
12.8 |
|
|
55–60 (57.2) |
15.3 |
14.9 |
|
|
≥ 60 (63.9) |
18.2 |
17.4 |
|
|
55–75 (60.2)b |
16.6 |
16.0 |
|
|
|
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|
aThe average GC content (%) in the subcategory of intergenic regions. bThis GC content bin was included for the comparison with the CpG island category. |
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|
Jiang and Zhao BMC Genomics 2006 7:316 doi:10.1186/1471-2164-7-316 |
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