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Open AccessResearch article

Directionality of point mutation and 5-methylcytosine deamination rates in the chimpanzee genome

Cizhong Jiang1 email and Zhongming Zhao1,2 email

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, P.O. Box 980126, Richmond, VA 23298-0126, USA

Center for the Study of Biological Complexity, Virginia Commonwealth University, Richmond, VA 23284, USA

author email corresponding author email

BMC Genomics 2006, 7:316doi:10.1186/1471-2164-7-316

Published: 13 December 2006

Additional files

Additional file 1:

Frequencies of nucleotide changes in intergenic regions. Supplementary Table S1 – Frequencies (%) of nucleotide changes in intergenic regions.

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Additional file 2:

Linear regression of the frequency of nucleotide changes versus GC content in intergenic regions. Supplementary Figure S1 – Linear regression of the frequency of each type of nucleotide changes versus GC content in intergenic regions.

Format: PDF Size: 16KB Download file

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Additional file 3:

Frequency difference of nucleotide changes between chimpanzees and humans in each genomic category. Supplementary Figure S2 – Frequency difference of nucleotide changes between chimpanzees and humans in each genomic category.

Format: PDF Size: 17KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional file 4:

Frequency difference of nucleotide changes for each pair of syntenic chimpanzee and human chromosomes. Supplementary Figure S3 – Frequency difference of nucleotide changes for each pair of syntenic chimpanzee and human chromosomes.

Format: PDF Size: 20KB Download file

This file can be viewed with: Adobe Acrobat Reader


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