Resolution:
## Figure 7.
Allele frequencies in the offspring pool predicted by pooled analysis and corrected
with
k (y-axis), plotted against the true allele frequencies of this sample (x-axis). The
correlation coefficient is r = 0.997. Note that the coefficient k was derived from parental data (see methods) and then applied to the data obtained
for children. Any errors in estimating the parental allele frequencies are incorporated
in the estimate of k and therefore the estimate of the allele frequency in offspring includes the measurement
errors from both samples.
Kirov |