Allele frequencies in offspring (uncorrected with k for bias in allele representation) predicted by pooled analysis (y-axis) plotted against the true allele frequencies obtained by individual genotyping of all subjects from whom the pool was derived (x-axis). The correlation coefficient is r = 0.961. True frequency differences are plotted in intervals of 0.0083 which corresponds to increments of one allele in the 30 offspring.
Kirov et al. BMC Genomics 2006 7:27 doi:10.1186/1471-2164-7-27