Table 1

Patients' characteristics.
patient
 age/sex
 diagnosis
 PNH-clone
 source of sample
 pre-therapy sample
 post-therapy sample
 pool
1
 19/F
 SAA
 n
 PB
BM
 y
y
 n
n
 I
I
2
 57/M
 vSAA
 n
 PB
BM
 y
y
 n
n
 I
I
3
 40/F
 SAA
 n
 PB
BM
 y
y
 n
n
 I
I
4
 70/F
 SAA
 n
 PB
BM
 y
y
 n
n
 I
I
5
 64/M
 SAA
 n
 PB
BM
 y
y
 y
y
 IIa/IIb
IIa/IIb
6
 70/F
 vSAA
 n
 PB
BM
 y
y
 y
y
 IIa/IIb
IIa/IIb

Abbreviations: F = female; M = male; (v)SAA = (very) severe aplastic anemia; n = no; y = yes; PB = peripheral blood; BM = bone marrow; I = pool I at initial presentation (n = 4); IIa = pool II at initial presentation (n = 2); IIb = pool II in hematological remission (n = 2). Disease classification was performed according to the International Study of Aplastic Anemia and Agranulocytosis [45].

Franzke et al. BMC Genomics 2006 7:263   doi:10.1186/1471-2164-7-263