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Cis-regulatory variations: A study of SNPs around genes showing cis-linkage in segregating mouse populations

Debraj GuhaThakurta*, Tao Xie, Manish Anand, Stephen W Edwards, Guoya Li, Susanna S Wang and Eric E Schadt*

BMC Genomics 2006, 7:235 doi:10.1186/1471-2164-7-235

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Serious limitations of the QTL/Microarray approach for QTL gene discovery

Ricardo A Verdugo, Charles R Farber, Craig H Warden, Juan F Medrano BMC Biology 2010, 8:96 (12 July 2010)

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Extent of differential allelic expression of candidate breast cancer genes is similar in blood and breast

Ana-Teresa Maia, Inmaculada Spiteri, Alvin JX Lee, Martin O'Reilly, Linda Jones, Carlos Caldas, Bruce AJ Ponder Breast Cancer Research 2009, 11:R88 (10 December 2009)

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Overexpression of Scg5 increases enzymatic activity of PCSK2 and is inversely correlated with body weight in congenic mice

Charles R Farber, James Chitwood, Sang-Nam Lee, Ricardo A Verdugo, Alma Islas-Trejo, Gonzalo Rincon, Iris Lindberg, Juan F Medrano BMC Genetics 2008, 9:34 (25 April 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The molecular chaperone gene Secretogranin 5 (Scg5) affects body weight in mice by acting on the enzyme prohormone convertase 2 (PCSK2), with QTL analysis showing Scg5 expression levels probably being modulated by polymorphisms in the Scg5 promoter.

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