Semiparametric approach to characterize unique gene expression trajectories across time

Sandra L Rodriguez-Zas¹^,2^,3 , Bruce R Southey¹^,4^,5 , Charles W Whitfield³^,6 and Gene E Robinson³^,6

¹Department of Animal Sciences, University of Illinois at Urbana-Champaign, IL 61801, USA

²Department of Statistics, University of Illinois at Urbana-Champaign, IL 61801, USA

³Institute for Genomic Biology, University of Illinois at Urbana-Champaign, IL 61801, USA

⁴Department of Chemistry, University of Illinois at Urbana-Champaign, IL 61801, USA

⁵Department of Computer Science, University of Illinois at Urbana-Champaign, IL 61801, USA

⁶Department of Entomology, University of Illinois at Urbana-Champaign, IL 61801, USA

author email corresponding author email

BMC Genomics 2006, 7:233doi:10.1186/1471-2164-7-233


Published:	13 September 2006

Additional files

Additional File 1:

Apis mellifera (honey bee) gene identification (GB prefix), Drosophila (fruit fly) homologous (CG prefix), semiparametric group membership and Gene Ontology (GO) information of 54 genes with neurobiological function in the mellifera (M) data set and in the ligustica (L) data set if different from M. This table provides the functional classification, honeybee gene identification, corresponding fruit fly gene identification, Gene Ontology description and, semiparametric group assignment in the mellifera (M) and ligustica (L) data sets of 54 genes with neurobiological function studied.

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Additional File 2:

List of 25 cDNAs with significant (P < 0.00001) linear or quadratic or cubic profiles from day 0 (nurse) to day 17 (forager), estimate of expression at each day in the ligustica (L) and mellifera (M) data sets, gene group, and the relative expression between forager and nurse (FvsN) bees reported by Whitfield et al. (2003). This table provides a list with the identification of 25 cDNAs with significant linear, quadratic or cubic trends across days, the estimated gene expression at each day, semiparametric group, and the relative expression between forager and nurse bees reported in Whitfield et al. (2003) for the L and M data sets.

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Additional File 3:

Confidence interval limits (95%) of the expected cDNA expression trajectories for each of the 10 groups identified in the ligustica (L) data set. The legend indicates the group number and lower (lc) or upper (uc) confidence interval limits per group. The figure presents the 95% confidence interval limits of the expected cDNA expression trajectories for each of the 10 groups identified in the L data set.

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Additional File 4:

Confidence interval limits (95%) of the expected cDNA expression trajectories for each of the 10 groups identified in the mellifera (M) data set. The legend indicates the group number and lower (lc) or upper (uc) confidence interval limits per group. The figure presents the 95% confidence interval limits of the expected cDNA expression trajectories for each of the 10 groups identified in the M data set.

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Additional File 5:

L data set. L data set estimates per cDNA and age.

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Additional File 6:

M data set. M data set estimates per cDNA and age.

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