Table 2

Comparison of our gene list with gene lists described in literature

Reference: Cell lines
A2780 vs. CP70 + C30 + C200
CP70 vs. C30 + C200



Up-regulated
Down-regulated
Down-regulated*

[13]: 6 cisplatin resistant cell pairs, including A2780 and CP70
JUN (↑) and IFITM1 (↓)
MRC2(↓)

[14]: A2780 and oxaliplatin resistant C10B
FER1L3 (↑), LIPA (↑), IFITM1 (↑), NMI (↑) and ALCAM (↑)
SOC2 (↓), MID1(↓), TFPI (↓), MMRN (↓), CCR1 (↓) and NID2 (↑)
MMP3 (↑), SPARC (↑), FER1L3 (↑), TM4SF1 (↓), CRIM1 (↓) and PEG10 (↓)
[16]: 4 oxaliplatin resistant cell pairs, including A2780 and R4
NFE2L1 (↑), IFITM1 (↓)
TIP120B (↑)
TIMP2 (↑), COTL1 (↑), IL1R1 (↑), SPARC (↑) and SLC4A2 (↓)
[15]: A2780, cisplatin resistant ACR6 and ACRP

S100A11 (↓) and SLC25A6 (↓)
PEG10 (↑), TMSB4X (↓) and COL5A2 (↓)

The arrows behind the genes indicate whether the gene was up-regulated (↑) or down-regulated (↓) in the cisplatin/oxaliplatin resistant subline(s) compared to the cisplatin/oxaliplatin sensitive parental cell line according to microarray or SAGE data of other groups. * The genes selected from factor 2 that were also described in literature were all down-regulated in C30 + C200 compared to CP70.

Crijns et al. BMC Genomics 2006 7:232   doi:10.1186/1471-2164-7-232