Table 4

The top 25 genes exhibiting increased mRNA abundance 2 hours post activation.

Clone
E value
Accession No.
Gene Symbol
Gene
Fold Increase
FDRmax
P value

pIL8
0.0
NM_173925
IL8
Interleukin 8
40.00
1.23E-18
4.91E-22
MARC_3BOV_60P17
0.0
NM_174299
CXCL2
Chemokine (C-X-C motif) ligand 2 (GROβ/MIP2A)
38.20
1.25E-15
1.24E-18
C0006019e20
0.0
NM_181015
PRNP
Prion protein
28.13
1.05E-20
2.08E-24
MARC_1BOV_101M3
0.0
NM_174263
CCL20
Chemokine (C-C motif) ligand 20 (MIP3A)
25.81
3.14E-10
3.56E-12
MARC_1BOV_94L3
0.0
NM_174300
CXCL6
Chemokine (C-X-C motif) ligand 6
22.91
1.72E-11
1.23E-13
C0005209b8
6.00E-72
XM_612426
CCRN4L
CCR4 carbon catabolite repression 4-like
20.49
1.64E-11
1.14E-13
C0006018n14
0.0
NM_174006
CCL2
Chemokine (C-C motif) ligand 2 (MCP-1)
19.45
1.32E-07
4.19E-09
C0005204j16
0.0
XM_864683
CXCL3
Chemokine (C-X-C motif) ligand 3 (GROγ/MIP2b)
18.16
1.20E-13
3.40E-16
C0006020d11
0.0
XM_865242
ZFAND2A
Zinc finger, AN1-type domain 2A
17.61
1.10E-14
1.31E-17
C0006011e13
e-179
CK976904
-
EST
16.71
3.10E-08
8.41E-10
C0005208k22
e-167
NM_173198
NR4A3
Nuclear receptor subfamily 4, group A, member 3
15.65
2.39E-12
1.14E-14
C0006020e20
0.0
CB419326
-
EST
14.07
9.10E-12
5.60E-14
MARC_3BOV_36F6
0.0
NM_175827
CCL5
Chemokine (C-C motif) ligand 5 (RANTES)
13.84
2.90E-12
1.47E-14
C0006018g13
0.0
XM_611249
SLCO4A1
Solute carrier organic anion transporter family, member 4A1
13.79
4.62E-10
5.89E-12
MARC_1BOV_72M12
0.0
XM_866821
CXCL10
Chemokine (C-X-C motif) ligand 10 (IP10)
13.71
1.09E-05
6.09E-07
C0005199c13
0.0
AY248754
TNFAIP3
TNF-alpha induced protein 3
13.48
2.34E-08
5.90E-10
C0006015e11
0.0
XM_881561
PMAIP1
Phorbol-12-myristate-13-acetate-induced protein 1
12.99
1.95E-12
8.90E-15
C0005202i8
0.0
XM_583725
APOBEC3A
Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
12.96
1.20E-13
2.97E-16
MARC_3BOV_120N21
0.0
NM_174028
CSF3
Colony stimulating factor 3 (granulocyte) (G-CSF)
12.76
8.11E-11
7.73E-13
C0006015n15
2.00E-69
NM_002748
MAPK6
Mitogen-activated protein kinase 6 (erk-3)
12.64
8.88E-12
5.11E-14
C0006016h15
0.0
XM_613370
RGS1
Regulator of G-protein signalling 1
12.59
5.10E-09
1.00E-10
C0006013p15
e-158
CB534198
-
EST
12.59
1.93E-11
1.50E-13
C0005202d9
0.0
XM_870158
ANKRD22
Ankyrin repeat domain 22
11.99
6.36E-17
3.79E-20
MARC_1BOV_57B12
0.0
NM_174348
ICAM1
Intercellular adhesion molecule 1 (CD54)
11.40
6.40E-10
9.15E-12
C0005206b23
3.00E-82
NM_001432
EREG
Epiregulin
10.98
1.98E-07
6.61E-09

Summary of the top 25 genes exhibiting increased mRNA abundance 2 hours post activation, including clone name, accession number, e-value and identity of the best BLAST match and average fold change. The P and FDRmax values denote the probability from the moderated t-test and the Benjamini and Hochberg false discovery rate values respectively from the analysis of the resting cell values compared to the average activated sample values (Pre v Post).

Jensen et al. BMC Genomics 2006 7:224   doi:10.1186/1471-2164-7-224