Finding function: evaluation methods for functional genomic data

Chad L Myers¹^,2 , Daniel R Barrett¹^,2 , Matthew A Hibbs¹^,2 , Curtis Huttenhower¹^,2 and Olga G Troyanskaya¹^,2

¹Department of Computer Science, Princeton University, Princeton, NJ 08544, USA

²Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton NJ, 08544, USA

author email corresponding author email

BMC Genomics 2006, 7:187doi:10.1186/1471-2164-7-187


Published:	25 July 2006

Additional files

Additional File 1:

Biological expert voting results. This file contains the results of the voting procedure used to generate a functional gold standard based on the Gene Ontology (described in detail in Methods). Experts selected terms that are specific enough to direct laboratory experiments, but are also general enough to reasonably expect high-throughput assays to provide relevant information.

Format: TXT Size: 464KB Download file

Additional File 2:

Non-redundant set of specific GO terms. This file contains a non-redundant set of GO terms receiving more than 3 votes (of 6) from experts. The non-redundant set was obtained by removing any term whose ancestor in the hierarchy is also in the set.

Format: TXT Size: 13KB Download file

Additional File 3:

Supplementary discussion. This file contains a more detailed discussion of the relative size of gold standard positive and negative example sets and associated issues.

Format: PDF Size: 109KB Download file

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