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Open AccessHighly AccessResearch article

Comparative analysis of cancer genes in the human and chimpanzee genomes

Xose S Puente1 email, Gloria Velasco1 email, Ana Gutiérrez-Fernández1 email, Jaume Bertranpetit2 email, Mary-Claire King3 email and Carlos López-Otín1 email

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, 33006-Oviedo, Spain

Unitat de Biologia Evolutiva, Departament de Ciencies Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain

Departments of Medicine and Genome Sciences, School of Medicine, University of Washington, Seattle WA-98195, USA

author email corresponding author email

BMC Genomics 2006, 7:15doi:10.1186/1471-2164-7-15

Published: 26 January 2006

Additional files

Additional data file 1:

Human and chimpanzee cancer genes comparison. This file contains the complete list of human and chimpanzee cancer genes, and comparison at the nucleotide and protein level.

Format: XLS Size: 1.5MB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional data file 2:

Chimpanzee cancer gene products identical to human orthologs. List of human genes identical to chimpanzee orthologs. Gene name, accession number, chromosomal location, protein length and functional category are indicated.

Format: DOC Size: 140KB Download file

This file can be viewed with: Microsoft Word Viewer

Additional data file 3:

Frameshifts in chimpanzee cancer genes. List of chimpanzee cancer genes for which frameshifts or premature stop codons are present in the ARACHNE assembly, as well as the correct sequence obtained by direct sequencing or comparison with the PCAP assembly.

Format: XLS Size: 33KB Download file

This file can be viewed with: Microsoft Excel Viewer


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