BMC Genomics

official impact factor 4.21

Open Access Research article

The majority of genes in the pathogenic Neisseria species are present in non-pathogenic Neisseria lactamica, including those designated as 'virulence genes'

Lori AS Snyder* and Nigel J Saunders

Author Affiliations

Bacterial Pathogenesis and Functional Genomics Group, Sir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, UK

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BMC Genomics 2006, 7:128 doi:10.1186/1471-2164-7-128

Published: 30 May 2006

Additional files

Additional file 2:

Genes from the pathogenic Neisseria spp. present in one or more of 13 N. lactamica strains. This file contains a table of all of those genes for which the associated pan-Neisseria microarray-v2 probe was hybridized by at least one of the N. lactamica strains tested. The number of strains with positive hybridizations is indicated.

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Open Data

Additional file 3:

Probe content and design for the pan-Neisseria microarray, versions 1 & 2. This file provides a detailed description of the design and construction of the pan-Neisseria microarray and the revised and updated pan-Neisseria microarray-v2. Included are details of the probe design and selection criteria, the sequences against which the microarray was designed, additions to the microarray in version 2, and publications that have used the pan-Neisseria microarray in CGH.

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Open Data

Additional file 1:

Virulence-associated and predicted virulence-associated genes from the pathogenic Neisseria spp. This file contains a table of those genes from the current published literature that have been suggested to have a role in virulence. Genes for which there were positive hybridizations on the pan-Neisseria microarray-v2 in the N. lactamica strains tested are indicated, as are those genes present in all four of the currently available Neisseria spp. genome sequences.

Format: PDF Size: 19KB Download file

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Open Data