Table 7

Differentially expressed candidate genes from microarray experiments mapped in silico to autism susceptibility genes and QTL

Candidate gene

Genbank #

Physical Location

Reported closely mapped autism candidate genes or QTL*

Ref


ASS

AA676405

chr9 (130,349,862–130,406,214)

dopamine beta-hydroxylase (9q34)

77

CHL1

H15267

chr3 (423,533–426,095)

KIAA0121 (3p25.2)

75

IL6R-beta, gp130

T61343

chr5 (55,267,950–55,272,766)

Language QTL chr5:40(0–67)

76

IL6ST

AA406546

chr5 (55,271,809–55,272,305)

Language QTL chr5:40(0–67)

76

DAPK1

AI371096

chr9 (87,552,642–87,553,099)

FLAP, ALOX5AP

T49652

chr13 (30,207,643–30,236,962)

AUTS3 (13q14-22), HTR2A-2 (serotonin recep. 2A) (13q14-21)

71, 72

ITGB7

AI380522

chr12 (51,871,361–51,887,333)

arginine vasopressin receptor 1A (12q14-15)

69

EGR2

AA446027

chr10 (64,241,755–64,246,081)

Language QTL chr10:107(72–126); HTR-7

76

ROBO1

AA173755

chr3 (78,729,082–78,729,496)


Hu et al. BMC Genomics 2006 7:118   doi:10.1186/1471-2164-7-118

Open Data