Figure 4.

CD8+ T-cell signature genes. Relative expression of CD8+ T-cell signature genes is shown for all samples. Genes (rows) are sorted in descending order of correlation of gene expression with relative abundance of T-cells. Samples (columns) are ordered in decreasing relative abundance from left to right. The grayscale bar on top shows the estimated relative abundance of CD8+ T-cells in each class of samples – black indicates 100% relative abundance of CD8+ T-cells, white indicates 0% relative abundance of CD8+ T-cells, and grey indicates intermediate relative abundance of CD8+ T-cells. Gene expression values are centered across all samples to a median of zero. All genes mentioned in the text are listed and their position is marked with a black bar.