Conserved genes in a path from commensalism to pathogenicity: comparative phylogenetic profiles of Staphylococcus epidermidis RP62A and ATCC12228

doi:10.1186/1471-2164-7-112

BMC Genomics

Volume 7

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Cao ZW
Zhu YL
Wang XJ
Ding GH
Xu H
Jia PL
Qu D
Danchin A
Li YX

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Li YX
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Research article

Conserved genes in a path from commensalism to pathogenicity: comparative phylogenetic profiles of Staphylococcus epidermidis RP62A and ATCC12228

Wu Wei¹^,2^* , ZhiWei Cao²^* , Yu-Li Zhu³ , XiaoJing Wang¹^,2 , GuoHui Ding¹ , Hao Xu² , PeiLin Jia¹^,2 , Di Qu³ , Antoine Danchin⁴ and YiXue Li¹^,2

¹Bioinformatics Center, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences; Graduate School of the Chinese Academy of Sciences, 320 YueYang Road, Shanghai, China

²Shanghai Center for Bioinformation Technology, 100 Qinzhou Road, Shanghai, China

³Department of Medical Molecular Virology, Institute of Medical microbiology, Shanghai Medical School of Fudan University, 138 YiXue Yuan Road, Shanghai, China

⁴Genetics of Bacterial Genomes/URA 2171 CNRS, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France

author email corresponding author email* Contributed equally

BMC Genomics 2006, 7:112doi:10.1186/1471-2164-7-112


Published:	10 May 2006

Additional files

Additional File 1:

Distribution of insertions in either of the two sequenced Staphylococcus epidermidis genomes.

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Additional File 2:

Distribution of orthologs of two Staphylococcus epidermidis strains.

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Additional File 3:

Ratios of non-synonymous vs synonymous of orthologs with SNPs pairs of Virulence factors.

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Additional File 4:

Ratios of non-synonymous vs synonymous of orthologs with SNPs pairs of Surface proteins.

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Additional File 5:

Ratios of non-synonymous vs synonymous of orthologs with all SNPs pairs.

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Additional File 6:

Comparison the sensitivity to H₂O₂of both Staphylococcus epidermidis strains. Each bar represents the OD₅₉₅value of one strain at specific time and concentration of H₂O₂.

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Additional File 7:

Comparison the sensitivity to H₂O₂(5%) of both Staphylococcus epidermidis strains. Red bars represent the OD₅₉₅value of S. epidermidis RP62A at different time and blue bars represent S. epidermidis ATCC12228.

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Additional File 9:

Comparison of identical and non-identical distribution of different functional groups of orthologous genes.

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Additional File 8:

Primers used in the PCR experiments.

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