BMC Genomics

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Positional and functional mapping of a neuroblastoma differentiation gene on chromosome 11

Katleen De Preter*, Jo Vandesompele, Björn Menten, Philippa Carr, Heike Fiegler, Anders Edsjö, Nigel P Carter, Nurten Yigit, Wim Waelput, Nadine Van Roy, Scott Bader, Sven Påhlman and Frank Speleman

BMC Genomics 2005, 6:97 doi:10.1186/1471-2164-6-97

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Research article   Open Access

CADM1 is a strong neuroblastoma candidate gene that maps within a 3.72 Mb critical region of loss on 11q23

Evi Michels, Jasmien Hoebeeck, Katleen De Preter, Alexander Schramm, Bénédicte Brichard, Anne De Paepe, Angelika Eggert, Geneviève Laureys, Jo Vandesompele, Frank Speleman BMC Cancer 2008, 8:173 (17 June 2008)

BAC array analysis of chromosome 11 status on both primary tumors and cell ines and meta-analysis of expression profiles of 692 neuroblastoma samples suggest that CADM1 is a potential neuroblastoma suppressor gene.