Table 2

Frequency and number of DR3-positive haplotypes estimated by the Arlequin software.

T1D (2n = 596)

Controls (2n = 1006)


Freq.

Haplotypes

Freq.

Haplotypes

DR3-Total

0.39432

235

0.13120

132

I. DR3-a1b5

0.17276

103

0.03802

38

II. DR3-a2b3

0.10244

61

0.04866

49

III. DR3-other

0.11912

71

0.04452

45


I vs. II+III. OR = 1.93 (1.19–3.13); p = 0.004.

I vs. II. OR = 2.18 (1.24–3.83); p = 0.004.

I vs. III. OR = 1.72 (0.98–3.01); p = 0.043.

II vs. III. OR = 0.79 (0.45–1.39); p = 0.38.

Urcelay et al. BMC Genomics 2005 6:56   doi:10.1186/1471-2164-6-56

Open Data