Gene trees displaying the microarray generated expression profiles of abdomen-derived cDNAs in blood-fed compared to sugar-fed adult female mosquitoes during the following times: 5 and 30 minutes during blood meal (DBM), 0, 1, 3, 5, 12, 16, 24, and 48 hours post blood meal (PBM). k-means clustering of all genes up-regulated and down-regulated at least two-fold during at least one of the ten time points generated three sets of genes. These k-means-derived groups of genes were hierarchically clustered for visualization and include Set 1 designated the Early Genes (A), Set 2 designated the Middle Genes (B), and Set 3 designated the Late Genes (C). Each gene is represented by a single row of colored boxes; each time point is represented as a single column of colored boxes. The expression scale is represented as a gradation of color ranging from 5 fold induced genes indicated by saturated red to 2.5 fold repressed genes indicated by saturated green.
Dana et al. BMC Genomics 2005 6:5 doi:10.1186/1471-2164-6-5