Table 2 |
|||||||
|
Transcripts identified as over-expressed in ERα (+) breast cancers commonly detected by cross-platforms comparison (SAGE and oligonucleotide microarrays). |
|||||||
|
Gene name |
Locus Link ID |
Fold change |
Frequency |
Gene name |
Locus Link |
Fold change |
Frequency# |
|
|
|||||||
|
TFF1* |
7031 |
51.4 |
15/18 (83%) |
SULF2 |
55959 |
2.9 |
11/18 (61%) |
|
SYTL4* |
94121 |
28.0 |
15/18 (83%) |
THBS4 |
7060 |
2.9 |
8/18 (44%) |
|
DUSP4 |
1846 |
14.7 |
14/18 (78%) |
AZGP1 |
563 |
2.8 |
9/18 (50%) |
|
NAT1 |
9 |
11.7 |
15/18 (83%) |
BBC3* |
27113 |
2.8 |
12/18 (67%) |
|
ECM1* |
1893 |
10.1 |
13/18 (72%) |
NET7* |
23555 |
2.8 |
10/18 (55%) |
|
KIAA0882 |
23158 |
10.1 |
18/18 (100%) |
NET6 |
27075 |
2.8 |
12/18 (67%) |
|
JDP1 |
56521 |
10.0 |
12/18 (67%) |
TRAF5 |
7188 |
2.8 |
9/18 (50%) |
|
ESR1 |
2099 |
9.8 |
18/18 (100%) |
BTG2 |
7832 |
2.7 |
9/18 (50%) |
|
HDGFRP3 |
50810 |
9.8 |
12/18 (67%) |
RNF123* |
63891 |
2.7 |
11/18 (61%) |
|
TCEAL1 |
9338 |
9.8 |
13/18 (72%) |
CHAD* |
1101 |
2.6 |
12/18 (67%) |
|
TSPAN1* |
10103 |
9.5 |
15/18 (83%) |
CSNK1A1 |
1452 |
2.6 |
14/18 (78%) |
|
C20orf103* |
24141 |
9.3 |
10/18 (55%) |
EVL |
51466 |
2.6 |
12/18 (67%) |
|
MYLIP |
29116 |
9.3 |
11/18 (61%) |
HIST1H2BD |
3017 |
2.6 |
10/18 (55%) |
|
ABCA3 |
21 |
8.9 |
10/18 (55%) |
SUSD3 |
203328 |
2.6 |
9/18 (50%) |
|
SEC14L2 |
23541 |
8.7 |
9/18 (50%) |
PLAT* |
5327 |
2.6 |
8/18 (44%) |
|
ANXA9* |
8416 |
8.4 |
10/18 (55%) |
RARRES3* |
5920 |
2.6 |
11/18 (61%) |
|
KCTD3 |
51133 |
8.4 |
17/18 (94%) |
SH3BGRL* |
6451 |
2.6 |
8/18 (44%) |
|
SCUBE2 |
57758 |
7.5 |
14/18 (78%) |
TPBG* |
7162 |
2.6 |
9/18 (50%) |
|
ITGBL1 |
9358 |
7.1 |
8/18 (44%) |
UGCG |
7357 |
2.6 |
11/18 (61%) |
|
C14orf168 |
83544 |
6.7 |
6/18 (33%) |
CELSR2* |
1952 |
2.5 |
8/18 (44%) |
|
FBP1 |
2203 |
6.7 |
14/18 (78%) |
CRIM1 |
51232 |
2.5 |
11/18 (61%) |
|
MYB |
4602 |
6.7 |
14/18 (78%) |
FLJ90798* |
219654 |
2.5 |
9/18 (50%) |
|
RARA* |
5914 |
6.7 |
12/18 (67%) |
KIF12 |
113220 |
2.5 |
7/18 (39%) |
|
CaMKIINα |
55450 |
6.3 |
18/18 (100%) |
LRIG1 |
26018 |
2.5 |
9/18 (50%) |
|
AR* |
367 |
6.2 |
10/18 (55%) |
LRP2* |
4036 |
2.5 |
10/18 (55%) |
|
ZNF552 |
79818 |
6.2 |
16/18 (89%) |
PHF15* |
23338 |
2.5 |
12/18 (67%) |
|
MIPEP* |
4285 |
6.0 |
14/18 (78%) |
HSMNP1 |
55861 |
2.4 |
8/18 (44%) |
|
BAI2 |
576 |
5.3 |
15/18 (83%) |
LOC123169 |
123169 |
2.4 |
12/18 (67%) |
|
DP1L1 |
92840 |
5.3 |
15/18 (83%) |
PINK1* |
65018 |
2.4 |
11/18 (61%) |
|
VAV3 |
10451 |
5.3 |
12/18 (67%) |
PRKAR2B |
5577 |
2.4 |
7/18 (39%) |
|
KIAA0089 |
23171 |
5.2 |
17/18 (94%) |
TJP3* |
27134 |
2.4 |
11/18 (61%) |
|
GATA3 |
2625 |
5.1 |
15/18 (83%) |
CCND1 |
595 |
2.3 |
9/18 (50%) |
|
QDPR |
5860 |
5.1 |
11/18 (61%) |
CYBRD1 |
79901 |
2.3 |
10/18 (55%) |
|
C1orf21 |
81563 |
4.9 |
11/18 (61%) |
KRT18 |
3875 |
2.3 |
10/18 (55%) |
|
KIAA1143 |
57456 |
4.9 |
7/18 (39%) |
PURA |
5813 |
2.3 |
9/18 (50%) |
|
OIP106 |
22906 |
4.9 |
16/18 (89%) |
SREBF1* |
6720 |
2.3 |
10/18 (55%) |
|
AGR2 |
10551 |
4.6 |
10/18 (55%) |
CYB5R1 |
51706 |
2.2 |
6/18 (33%) |
|
MGC4251 |
84336 |
4.6 |
13/18 (72%) |
DLG3* |
1741 |
2.2 |
9/18 (50%) |
|
FER1L3 |
26509 |
4.4 |
10/18 (55%) |
EEF1A2 |
1917 |
2.2 |
11/18 (61%) |
|
C4A |
720 |
4.1 |
11/18 (61%) |
GSTZ1 |
2954 |
2.2 |
9/18 (50%) |
|
CRIP2 |
1397 |
4.0 |
15/18 (83%) |
LOC159090 |
159090 |
2.2 |
6/18 (33%) |
|
NTN4 |
59277 |
4.0 |
10/18 (55%) |
MGC11242* |
79170 |
2.2 |
10/18 (55%) |
|
GJA1 |
2697 |
3.8 |
11/18 (61%) |
MGC18216* |
145815 |
2.2 |
8/18 (44%) |
|
CGI-111* |
51015 |
3.7 |
14/18 (78%) |
NEIL1 |
79661 |
2.2 |
6/18 (33%) |
|
CROT* |
54677 |
3.6 |
15/18 (83%) |
XBP1* |
7494 |
2.2 |
8/18 (44%) |
|
DACH |
1602 |
3.6 |
13/18 (72%) |
IRX5 |
10265 |
2.1 |
8/18 (44%) |
|
DKFZP564D172 |
83989 |
3.6 |
10/18 (55%) |
RAB31 |
11031 |
2.1 |
9/18 (50%) |
|
FGD3 |
89846 |
3.6 |
10/18 (55%) |
SSBP2 |
23635 |
2.1 |
7/18 (39%) |
|
RNASE4* |
6038 |
3.6 |
12/18 (67%) |
TGFB3 |
7043 |
2.1 |
8/18 (44%) |
|
GLUL* |
2752 |
3.3 |
11/18 (61%) |
BMPR1B |
658 |
2.0 |
7/18 (39%) |
|
FOXA1 |
3169 |
3.2 |
10/18 (55%) |
FLJ21174 |
79921 |
2.0 |
6/18 (33%) |
|
MGC7036 |
196383 |
3.2 |
14/18 (78%) |
FLJ22386 |
79641 |
2.0 |
7/18 (39%) |
|
MUC1* |
4582 |
3.2 |
12/18 (67%) |
HSPB1* |
3315 |
2.0 |
6/18 (33%) |
|
NAV1 |
89796 |
3.1 |
13/18 (72%) |
IGFBP4* |
3487 |
2.0 |
8/18 (44%) |
|
RPLP1* |
6176 |
3.1 |
12/18 (67%) |
MGC15737* |
85012 |
2.0 |
8/18 (44%) |
|
ALCAM |
214 |
2.9 |
9/18 (50%) |
SPARCL1 |
8404 |
2.0 |
9/18 (50%) |
|
HSD17B4* |
3295 |
2.9 |
13/18 (72%) |
STARD10* |
10809 |
2.0 |
7/18 (39%) |
|
|
|||||||
|
* Genes with known or putative high-affinity EREs mapping in the vicinity of the TSS. # Transcripts tags changing > 2-fold when compared with the average expression of ERα (-) tumors. Underlined genes correspond to the transcripts cross-validated among all three compared platforms. |
|||||||
|
Abba et al. BMC Genomics 2005 6:37 doi:10.1186/1471-2164-6-37 |
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